Renal Physiology Thick Ascending Limb of the Loop of Henle
نویسنده
چکیده
The thick ascending limb occupies a central anatomic and functional position in human renal physiology, with critical roles in the defense of the extracellular fluid volume, the urinary concentrating mechanism, calcium and magnesium homeostasis, bicarbonate and ammonium homeostasis, and urinary protein composition. The last decade haswitnessed tremendous progress in the understanding of themolecular physiology and pathophysiology of this nephron segment. These advances are the subject of this review, with emphasis on particularly recent
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تاریخ انتشار 2014